Glucosamine functions to normalise cartilage metabolism and helps to repair damaged or eroded cartilage. It stimulates the production of glycoaminoglycans (GAGs), proteoglycans and collagen in the joint cartilage matrix and synovial fluid, all of which are important to prevent the breakdown of cartilage.
Chondroitin sulphate is a cartilage component that promotes water retention and elasticity. Acting like a water magnet, it absorbs water into connective tissue and provides shock absorption. Chondroitin is the most abundant GAGs in the articular cartilage. At the same time, it can also inhibit the enzymes in cartilage breakdown.
BiO-LiFE Glucosamine 500mg with Chondroitin Sulphate 400mg is formulated based on the dosage used in Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT) in 2006. The combination of glucosamine and chondroitin sulphate in the trial conducted over a period of 6 months demonstrated effectiveness in treating moderate to severe osteoarthritis knee pain compared to Non-Steroidal Anti-Infalmmatory Drugs (NSAIDs).
Light to moderate: One tablet twice daily, 15 minutes before meals for at least 6 weeks (or according to medical prescription).
Severe orthoarthritis symptoms: One tablet three times daily, 15 minutes before meals for at least 8 weeks
Follow-up therapy: Maintenance therapy should be followed for 3-4 months (or according to medical prescription) by administration of one tablet twice daily, 15 minutes before meals. The treatment should be repeated every other 6 months or less according to medical prescription.
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